[This is a repost of an article that appeared on May 24, 2007. Since Iâ€™m knee-deep in final projects and exams, I thought Iâ€™d pull out a popular article from the archives. I hope you enjoy it (again)]:
In Part I of the â€œYou and the $1000 Genomeâ€ series we examined the Archon X PRIZE for Genomics, a $10 million purse for the group that can sequence 100 genomes in 10 days for no more than $10,000/genome with an error rate below 0.001%. With todayâ€™s technology this goal is still a few years away.
But do we need an entire genomic sequence to obtain all the relevant medical information that our DNA contains? After all, 99.9% of my DNA is exactly the same as everyone elseâ€™s! Why sequence that 99.9% over and over and over if the results are the same every time? Wouldnâ€™t it be cheaper to just sequence and then decode the 0.1%?