Sharing Large Segments With a Match Does Not Validate Small Segments Shared With That Match

OK, that could be one of the worst blog titles I’ve written, but it’s intentional. When people share this post, I want the title to clearly convey the lesson.

Small Segments are Poison

We know that many small segments are false, and thus that many distant matches are false positives. I have written about small segments and distant matches many times. For a few background articles, see the following:

The (most current as of September 2017) definitive article on the nature of false versus true small segments is “Reducing Pervasive False-Positive Identical-by-Descent Segments Detected by Large-Scale Pedigree Analysis.” The paper is available online for free ( In the paper, the researchers found that more than 67% of all reported segments shorter than 4 cM are false-positive segments. At least 60% of 4cM segments were false-positive, and at least 33% of 5 cM segments were false-positive. The number of false-positives decreased fairly rapidly above 5 cM. See my analysis of this paper here.

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