Genealogy

If you’re serious about genetic genealogy, you’ve heard of GEDmatch. The third-party site is one of the few ways to compare testing results among the three testing companies. The site

However, since GEDmatch is run by two incredible volunteers (Curtis Rogers and John Olson) with full-time jobs, the site has experienced server issues and downtime. Many have lamented that there was no monetization plan in place, but gave donations in hope that it would help the site grow.

This week, GEDmatch announced a monetization strategy, namely advanced tools that are only available to Tier 1 members at a nominal cost of $10/month:

Basic GEDmatch programs remain free and we plan to keep them this way. Donations help cover the costs associated with running this site, and will provide you with the benefit of using the additional Tier 1 tools for a period of time equal to one month for every $10 donated. You may use the ‘Donate’ button below, for a one-time donation of any amount, or the ‘Join GEDmatch’ button to establish a recurring $10 per month amount. ... Click to read more!

In 2008, I wrote about the case of Mr. and Mrs. George Fry, who are believed to have brought a particularly negative mutation with them to the New World from Europe in 1630 (“A Single Colon Cancer Gene Traced to 1630 – The Future of Genetic Genealogy?“). The mutation – in the APC gene – increases the likelihood of colon cancer, and has been found in many of the Fry’s living descendants.

In this months’s issue of Nature Genetics (see “Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm“), researchers using the BALSAC Population Database traced a founder mutation in SGOL1, which causes Chronic Atrial and Intestinal Dysrhythmia, termed CAID syndrome. So not only is it interesting that the same gene is involved in both heart rhythm and intestinal rhythm, but that the DNA has been mapped to this ancestral couple. The couple, whose names were not provided, were married in France in 1620 and arrived shortly thereafter in Nouvelle France. ... Click to read more!

I’ve written before about a poster presented by AncestryDNA at the American Society of Human Genetics 2013 annual meeting, entitled “Reconstruction of Ancestral Human Genomes from Genome-Wide DNA Matches.”  In the abstract, the group describes how they use sequencing information from hundreds of descendants of an 18th century couple to recreate portions of the genomes of that couple.

AncestryDNA’s 2014 ASHG Poster 

The AncestryDNA group has continued to refine the process of reconstructing the genomes of ancestral couples, and has a poster in this year’s American Society of Human Genetics annual meeting:

Title: Reconstruction of ancestral human haplotypes using genetic and genealogical data.

Author(s): J. M. Granka, R. E. Curtis, K. Noto, Y. Wang, J. K. Byrnes, M. J. Barber, N. M. Myres, C. A. Ball, K. G. Chahine ... Click to read more!

Yesterday, Family Tree DNA , the genetic genealogy arm of Gene by Gene, announced that it has processed over 1,000,000 DNA test kits for genealogy and anthropology purposes. Congratulations!

There are several sales available at Family Tree DNA that you might want to take advantage of, including the following:

Family Finder

Family Finder is an autosomal DNA test that compares your DNA to the DNA of other users in the ever-growing Family Tree DNA database. You can also use your Family Finder raw data at an incredible array of third-party tools, including GEDmatch and DNAGedcom, among others.

Although the test is normally $99, each Family Finder test is now $79 until June 17, 2014. The more family members you’ve tested and can compare your DNA to, the more information you’ll be able to glean from autosomal DNA. For example, I just had an aunt return her kit, and I’ll soon be able to compare her DNA to myself, my father, and her first cousin in order to answer even more of my family’s questions. ... Click to read more!

Judy Russell, the Legal Genealogist, noted on her blog today that registration for the Salt Lake Institute of Genealogy (“SLIG”) opens this Saturday, June 14^th, at 9:00 AM Mountain Daylight Time (11 a.m. Eastern, 10 a.m. Central, and 8 a.m. Pacific).

Regular readers of The Genetic Genealogist may not be familiar with SLIG, which is an institute run by the Utah Genealogical Association. SLIG is one of a very limited number of week-long institutes that offer educational content for genealogists. SLIG 2015 will be held at the Hilton Salt Lake City Center Hotel in Salt Lake City, Utah on January 12-16, 2015. Tuition for the institute is $375 for UGA members and $425 for everyone else.

This year there are 12 tracks at SLIG, including two at which I will be an instructor: ... Click to read more!